Molecular and pharmacological studies on signal transduction in the brain.
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چکیده
منابع مشابه
[Cellular and molecular pharmacological studies on membrane receptor-signaling and stress-responses in the brain].
Studies on the cellular and molecular mechanism of neurotransmitter receptor-signaling and of neuronal and glial cell responses to stresses seem to be important to elucidate the action mechanism of centrally-acting drugs and to develop novel therapeutics against several diseases in the brain. The present review shows our findings with regard to the membrane receptor-signaling mechanism includin...
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Introduction Good weather and a pint of apple juice (although we thought we had ordered beer) at a farmhouse opposite the European Molecular Biology Laboratory (EMBL) heralded the start of the 15th conference on ‘Oncogenes & Growth Control’. The participants had the opportunity to enjoy the friendly atmosphere at the EMBL, the hospitality of the staff and the tasty food. And of course, a series...
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چکیده ندارد.
15 صفحه اولMismatch repair, molecular switches, and signal transduction.
The foundation of molecular switches in biology is grounded in translation elongation and cellular signal transduction. In these systems, guanine nucleotidebound proteins (G proteins) produce the ON and OFF signaling states that act as gates for downstream biochemical processes. Recent studies on the human mismatch repair reaction have suggested a similar molecular switch that relies on adenine...
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In conditions of starvation, the free living amoebae of Dictyostelium enter a developmental program: The cells aggregate by chemotaxis to form a multicellular structure that undergoes morphogenesis and cell-type differentiation. These processes are mediated by a family of cell surface CAMP receptors (CARS) that act on a specific heterotrimeric G protein to stimulate actin polymerization, activa...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1996
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.107.9